Placental hormones and the control of fetal growth

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Placental hormones and the control of fetal growth

Linear growth in the postnatal period is controlled by the production, secretion, and action of pituitary growth hormone and IGF-1. IGF-I and IGF-II production and signaling are also essential for fetal growth and neural development. But the control of IGF production in the fetus is largely independent of GH. Among the factors that control fetal IGF production, the availability and utilization ...

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Fetal growth is a complex and dynamic process regulated by a large number of interactive factors of fetal, maternal, and placental origin. As a result, any abnormality of fetal growth has a complex multifactorial pathogenesis. It has been estimated that about 50% of intrauterine fetal growth is determined by fetal genes. Maternal disease, her nutritional intake and behaviours, such as smoking, ...

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BACKGROUND Worldwide, stillbirth is one of the leading causes of death. Altered fetal growth and placental abnormalities are the strongest and most prevalent known risk factors for stillbirth. The aim of this study was to identify patterns of association between placental abnormalities, fetal growth, and stillbirth. METHODS AND FINDINGS Population-based case-control study of all stillbirths a...

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ژورنال

عنوان ژورنال: International Journal of Pediatric Endocrinology

سال: 2015

ISSN: 1687-9856

DOI: 10.1186/1687-9856-2015-s1-o13